Platelet Rich Plasma (PRP) Skin Rejuvenation

A surgical procedure can bring both uneasiness and concern. Achieving the most favorable surgical outcome will be your main priority. Throughout the years, much research has been done on improving the healing of surgical wounds, which means minimising infection, swelling, pain, bruising, and scarring, while improving wound closure and incision lines. It is documented that Platelet Rich Plasma can be the single solution to all of these desired outcomes. Platelet Rich Plasma is 100% biocompatible and safe. It poses absolutely no infectious risk to the patient because it is made from the patient’s own plasma. No time consuming visits to the blood bank for pre-donation is required, and all the remarkable benefits of enhanced and superior wound healing is easily achieved for a markedly improved surgical outcome.

Platelets play an important role in wound healing. They provide initial hemostasis and release mediators to help modulate the inflammatory response and many of the cellular functions involved in wound healing. Contained in the alpha granules of platelets are multiple growth factors, which would include PDGF, TGF, PDAF, PDEGF, EGF, TNF, LDGF, FGF, CTGF along with many others. Growth factors are proteins that impart specific biochemical messages to specific target cells through specific membrane receptors. Growth factors possess paracrine related properties which are stimulatory for mitogenic activities, cellular differentiation, protein transcription, chemotaxis, angiogenesis, and collagenase activities. Tissue repair begins with a clot formation and platelet degranulation which release the growth factors necessary for wound repair. The chemotactic and proliferative effects of these cytokines cause the migration of neutrophils and macrophages, adding an antimicrobial component to the wound site. Angiogenesis, fibroplasia, and collagen synthesis, caused by growth factors, lead to rapid re-epithelization and increased wound tensile strength. PDGF may also act as an exogenous source of growth factors to help stimulate the anabolic activity of bone cells. Osteoblast-like cells have been shown to be sensitive to the proliferative action of a wide variety of growth factors. These growth factors have been isolated from platelets and bone and are locally released in response to injury.

PRP Skin Regeneration Therapy, a type of regenerative medicine with the patient’s own blood, uses components called platelets in the blood to rejuvenate the skin. Based on an innate wound-healing ability, the therapy is performed by injecting components collected from the blood and is associated with no risk of allergy or infections. Platelets contain substances called growth factors that activate and rejuvenate cells in the body. The growth factors, when released, induce the production of collagen and generation of new capillaries to rejuvenate the skin

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